This report summarizes the data collection and analytic methods and results for the 2012 Questionnaire Field Test (QFT) for the National Survey on Drug Use and Health (NSDUH). The 2012 QFT is meant to test the revisions to the questionnaire and protocols. These changes were designed to achieve three main goals: (1) to revise the questionnaire to address changing policy and research data needs, (2) to modify the survey methodology to improve the quality of estimates and the efficiency of data collection and processing, and (3) to maintain trends in core substance use estimates.